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Research

Combined treatment with lisofylline and exendin-4 reverses autoimmune diabetes Biochemical and Biophysical Research Communications; Copyright 2006 Elsevier, Inc.; Published April 5, 2006; doi:10.1016/j.bbrc.2006.03.173

Activation of the 12-Lipoxygenase and Signal Transducer and Activator of Transcription Pathway During Neointima Formation in a Model of the Metabolic Syndrome - Am J Physiol Endocrinol Metab (August 23, 2005). doi:10.1152/ajpendo.00133.2005

Inflammatory Blockade Improves Human Pancreatic Islet Function and Viability - American Journal of Transplantation 2005; 5:475-483 Blackwell Munksgaard (PDF)

Inflammation blockade improves pancreatic islet function - Transplant Proc. 2004 Nov;36(9):2864-5.

Autoimmune diabetes is blocked in Stat4-deficient mice - J Autoimmun. 2004 May;22(3):191-200.

Lisofylline, a novel anti-inflammatory agent, enhances glucose-stimulated insulin secretion in vivo and in vitro: studies in prediabetic and normal rats - Metabolism. 2004 Mar;53(3):290-6.

The novel anti-inflammatory agent lisofylline prevents autoimmune diabetic recurrence after islet transplantation - Transplantation. 2004 Jan 15;77(1):55-60.

Lisofylline, a Novel Antiinflammatory Compound, Protects Mesangial Cells from Hyperglycemia- and Angiotensin II-Mediated Extracellular Matrix Deposition - Endocrinology Vol. 144, No. 12 5227-5231 Copyright © 2003 by The Endocrine Society

The novel anti-inflammatory compound, lisofylline, prevents diabetes in multiple low-dose streptozotocin-treated mice - Pancreas. 2003 May;26(4):e99-104.

Lisofylline, a Novel Antiinflammatory Agent, Protects Pancreatic ß-Cells from Proinflammatory Cytokine Damage by Promoting Mitochondrial Metabolism - Endocrinology Vol. 143, No. 6 2341-2348
Copyright © 2002 by The Endocrine Society

The anti-inflammatory compound lisofylline prevents Type I diabetes in non-obese diabetic mice - Diabetologia. 2002 Sep;45(9):1307-14. Epub 2002 Aug 1
 

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